Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...
Patent
1981-12-11
1984-07-03
Ore, Dale R.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Bacterium or component thereof or substance produced by said...
424 14, 424 21, 424 32, 424168, 424170, 424357, A01N 4342, A61K 910, A61K 920
Patent
active
044579330
ABSTRACT:
This invention concerns a method for decreasing both the oral and parenteral abuse potential of strong analgetic agents such as oxycodone, propoxyphene and pentazocine by combining an analgesic dose of the analgetic agents with naloxone in specific, relatively narrow ranges. Oxycodone-naloxone compositions having a ratio of 2.5-5:1 parts by weight and pentazocine-naloxone compositions having a ratio of 16-50:1 parts by weight are preferred.
REFERENCES:
patent: 3254088 (1966-05-01), Lewenstein
patent: 3466277 (1969-09-01), Merz et al.
patent: 3493657 (1970-02-01), Lewenstein
patent: 3676557 (1972-07-01), Lachman et al.
patent: 3773955 (1973-11-01), Pachter
patent: 4126684 (1978-11-01), Robson et al.
Modern Drug Encyclopedia & Therapeutic Index, 8, 1975, pp. 550-551.
Hospital Formulary, vol. I, 1966, Sec. 28:08, Analgesics & Antipyretics.
Gordon Maxwell
Pachter Irwin J.
Bristol-Myers Company
Lloyd Richard R.
Ore Dale R.
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