Prevention and treatment of amyloidogenic disease

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Amino acid sequence disclosed in whole or in part; or...

Reexamination Certificate

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C424S001570, C424S009100, C424S009200, C424S193100, C424S197110, C424S236100, C436S086000, C436S507000, C514S021800, C530S324000, C530S327000, C530S329000, C530S330000

Reexamination Certificate

active

06982084

ABSTRACT:
The invention provides compositions and methods for treatment of amyloidogenic diseases. Such methods entail administering an agent that induces a beneficial immune response against an amyloid deposit in the patient. The methods are particularly useful for prophylactic and therapeutic treatment of Alzheimer's disease. In such methods, a suitable agent is Aβ peptide or an antibody thereto.

REFERENCES:
patent: 4666829 (1987-05-01), Glenner et al.
patent: 4713366 (1987-12-01), Stevens
patent: 5004697 (1991-04-01), Pardridge
patent: 5057540 (1991-10-01), Kensil et al.
patent: 5187153 (1993-02-01), Cordell et al.
patent: 5192753 (1993-03-01), McGeer et al.
patent: 5208036 (1993-05-01), Eppstein et al.
patent: 5220013 (1993-06-01), Ponte et al.
patent: 5231000 (1993-07-01), Majocha et al.
patent: 5231170 (1993-07-01), Averback
patent: 5270165 (1993-12-01), Van Nostrand et al.
patent: 5387742 (1995-02-01), Cordell
patent: 5434170 (1995-07-01), Andrulis, Jr.
patent: 5441870 (1995-08-01), Seubert et al.
patent: 5464823 (1995-11-01), Lehrer et al.
patent: 5571499 (1996-11-01), Hafler et al.
patent: 5571500 (1996-11-01), Hafler et al.
patent: 5958883 (1999-09-01), Snow
patent: 5985242 (1999-11-01), Findeis et al.
patent: 5989566 (1999-11-01), Cobb et al.
patent: 6057367 (2000-05-01), Stamler et al.
patent: 6114133 (2000-09-01), Seubert et al.
patent: 6150091 (2000-11-01), Pandolfo et al.
patent: 6262335 (2001-07-01), Hsiao et al.
patent: 6284221 (2001-09-01), Schenk et al.
patent: 6284533 (2001-09-01), Thomas
patent: 6294171 (2001-09-01), McMichael
patent: 6303567 (2001-10-01), Findeis et al.
patent: 6399314 (2002-06-01), Krishnamurthy
patent: 6417178 (2002-07-01), Klunk et al.
patent: 6562341 (2003-05-01), Prusiner et al.
patent: 2001/0018053 (2001-08-01), McMichael
patent: 2001/0021769 (2001-09-01), Prusiner
patent: 2002/0009445 (2002-01-01), Du et al.
patent: 2002/0077288 (2002-06-01), Frangione
patent: 2002/0086847 (2002-07-01), Chain
patent: 2002/0094335 (2002-07-01), Chalifour et al.
patent: 2002/0102261 (2002-08-01), Raso
patent: 2002/0132268 (2002-09-01), Chang et al.
patent: 2002/0133001 (2002-09-01), Gefter et al.
patent: 2002/0136718 (2002-09-01), Raso
patent: 2002/0160394 (2002-10-01), Wu
patent: 2002/0162129 (2002-10-01), Lannfelt
patent: 2002/0168377 (2002-11-01), Schaetzl
patent: 2002/0187157 (2002-12-01), Jensen et al.
patent: 2002/0197258 (2002-12-01), Ghanbari et al.
patent: 2003/0068325 (2003-04-01), Wang
patent: 2003/0073655 (2003-04-01), Chain
patent: 2003/0165496 (2003-09-01), Basi et al.
patent: 2003/0166558 (2003-09-01), Frangione et al.
patent: 451 700 (1991-10-01), None
patent: 276 723 (1993-12-01), None
patent: 613 007 (1994-08-01), None
patent: 666 080 (1995-08-01), None
patent: 359 783 (1995-11-01), None
patent: 683 234 (1995-11-01), None
patent: 440 619 (1996-01-01), None
patent: 526 511 (1997-05-01), None
patent: 782 859 (1997-07-01), None
patent: 783 104 (1997-07-01), None
patent: 594 607 (1997-08-01), None
patent: 845 270 (1998-06-01), None
patent: 863 211 (1998-09-01), None
patent: 868 918 (1998-10-01), None
patent: 652 962 (1998-12-01), None
patent: 911 036 (1999-04-01), None
patent: 561 087 (1999-08-01), None
patent: 639 081 (1999-11-01), None
patent: 506 785 (2000-03-01), None
patent: 1 172 378 (2002-01-01), None
patent: 2 220 211 (1990-01-01), None
patent: 2 335 192 (1999-09-01), None
patent: WO 88/10120 (1988-12-01), None
patent: WO 89/01343 (1989-02-01), None
patent: WO 89/03687 (1989-05-01), None
patent: WO 89/06242 (1989-07-01), None
patent: WO 89/06689 (1989-07-01), None
patent: WO 90/12870 (1990-11-01), None
patent: WO 90/12871 (1990-11-01), None
patent: WO 91/08760 (1991-06-01), None
patent: WO 91/12816 (1991-09-01), None
patent: WO 91/16819 (1991-11-01), None
patent: WO 91/19810 (1991-12-01), None
patent: WO 92/06187 (1992-04-01), None
patent: WO 92/06708 (1992-04-01), None
patent: WO 92/13069 (1992-08-01), None
patent: WO 93/02189 (1993-02-01), None
patent: WO 93/04194 (1993-03-01), None
patent: WO 93/14200 (1993-07-01), None
patent: WO 93/15760 (1993-08-01), None
patent: WO 93/16724 (1993-09-01), None
patent: WO 93/21950 (1993-11-01), None
patent: WO 94/01772 (1994-01-01), None
patent: WO 94/03615 (1994-02-01), None
patent: WO 94/28412 (1994-12-01), None
patent: WO 95/04151 (1995-02-01), None
patent: WO 95/05853 (1995-03-01), None
patent: WO 95/11008 (1995-04-01), None
patent: WO 95/11311 (1995-04-01), None
patent: WO 95/11994 (1995-05-01), None
patent: WO 95/12815 (1995-05-01), None
patent: WO 95/31996 (1995-11-01), None
patent: WO 96/18900 (1996-06-01), None
patent: WO 96/25435 (1996-08-01), None
patent: WO 96/28471 (1996-09-01), None
patent: WO 96/39176 (1996-12-01), None
patent: WO 97/10505 (1997-03-01), None
patent: WO 97/17613 (1997-05-01), None
patent: WO 97/21728 (1997-06-01), None
patent: WO 98/07850 (1998-02-01), None
patent: WO 98/44955 (1998-10-01), None
patent: WO 99/00150 (1999-01-01), None
patent: WO 99/06066 (1999-02-01), None
patent: WO 99/27911 (1999-06-01), None
patent: WO 99/27944 (1999-06-01), None
patent: WO 99/27949 (1999-06-01), None
patent: WO 99/06545 (1999-11-01), None
patent: WO 99/58564 (1999-11-01), None
patent: WO 99/60021 (1999-11-01), None
patent: WO 99/60024 (1999-11-01), None
patent: WO 01/62284 (2000-03-01), None
patent: WO 00/43039 (2000-07-01), None
patent: WO 00/43049 (2000-07-01), None
patent: WO 00/72870 (2000-12-01), None
patent: WO 00/72876 (2000-12-01), None
patent: WO 00/72876 (2000-12-01), None
patent: WO 00/72880 (2000-12-01), None
patent: WO 00/72880 (2000-12-01), None
patent: WO 00/77178 (2000-12-01), None
patent: WO 02/03911 (2001-04-01), None
patent: WO 01/39796 (2001-06-01), None
patent: WO 01/42306 (2001-06-01), None
patent: WO 01/62801 (2001-08-01), None
patent: WO 01/77167 (2001-10-01), None
patent: WO 01/90182 (2001-11-01), None
patent: WO 02/34777 (2002-05-01), None
patent: WO 02/34878 (2002-05-01), None
patent: WO 03/020212 (2003-03-01), None
Aguzzi et al., “Prion research: the next frontiers,”Nature,389:795-798 (1997).
Akiyama et al., “Inflammation and Alzheimer's disease,”Neurobiology of Aging,21:383-421 (2000).
Akiyama et al., “Occurrence of the Diffuse Amyloid β-Protein (Aβ) Deposits With Numerous Aβ-Containing Glial Cells in the Cerebral Cortex of Patients With Alzheimer's Disease,”Glia,25:324-331 (1999).
Andersen et al., “Do nonsteroidal anti-inflammatory drugs decrease the risk for Alzheimer's disease?”,Neurology,45:1441-1445 (1995).
Associated Press, “Immune cells may promote Alzheimer's a study finds,”The Boston Globe(Apr. 13, 1995).
Bard et al., “Peripherally administered antibodies against amyloid β-peptide enter the central nervous system and reduce pathology in a mouse model of Alzheimer disease,”Nature Medicine,6(8):916-919 (2000).
Barrow, et al., “Solution Conformations and aggregational Properties of Synthetic Amyloid Beta-Peptides of Alzheimer's Disease. Analysis of Circular Dichroism Spectra”,J. Mol. Biol.,225(4): 1075-1093 (1992).
Bauer et al., “Interleukin-6 and α-2-macroglobulin indicate an acute-phase state in Alzheimer's disease cortices,”FEBS Letters,285(1):111-114 (1991).
Beasley, “Alzheimer's traced to proteins caused by aging,” Reuters, Apr. 20, 2001 7:56 PM ET.
Benjamini and Leskowitz, fromImmunology A Short Course,Second Edition, Chapter 4, Antibody Structure, pp. 49-65, 1991, published by Wiley-Liss, New York, New York.
Bercovici et al., “Chronic Intravenous Injections of Antigen Induce and Maintain Tolerance in T Cell Receptor-Transgenic Mice,”Eur. J. Immunol.29:345-354 (1999).
Bickel et al., “Site Protected, Cationized Monoclonal Antibody Against Beta Amyloid as a Potential Diagnostic Imaging Technique for Alzheimer's Diseases,”Soc. for Neuroscience Abstracts18:764 (1992).
Blass, “Immunologic Treatment of Alzheimer's Disease,”New England J. Medicine,341 (22):1694 (1999).
Bodmer et al., “Transforming Growth Factor-Beta Bound to Soluble Derivativ

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