Drug – bio-affecting and body treating compositions – Whole live micro-organism – cell – or virus containing – Bacteria or actinomycetales
Patent
1997-03-17
2000-10-17
Naff, David M.
Drug, bio-affecting and body treating compositions
Whole live micro-organism, cell, or virus containing
Bacteria or actinomycetales
424 933, 4352524, 4352529, 435853, 435857, A01N 6300, C12N 100, C12N 120
Patent
active
061327107
ABSTRACT:
Gastrointestinal tissue injury and infections are treated by orally administering Lactobacilli strains. The Lactobacilli strains prevent neonatal necrotizing enterocolitis tissue injury and necrotizing enterocolitis in preterm infants. Preterm infants, full-term infants, children and adults as well as animals may be given the Lactobacilli strains. The strains are Lactobacillus salivarius strain ATCC 202196 and Lactobacillus plantarum strain ATCC 202195. Further, the strains may be given individually or as a combination of the two strains. In addition, the strains are useful in treating diarrhea. The Lactobacilli strains normalize and balance bacterial milieu in the gastro-intestinal tract. The Lactobacilli strains may be in lyophilized capsule form. The capsule may be an enteric coated slow-release microcapsule. The Lactobacilli strains may also be administered by means of a naso-gastric tube, especially for preterm infants.
REFERENCES:
patent: 4689266 (1987-08-01), Eckler
patent: 5411751 (1995-05-01), Crissinger et al.
patent: 5413785 (1995-05-01), Nanji
patent: 5439678 (1995-08-01), Dobrogosz et al.
Zetterstrom et al., Early Infant Feeding . . . , Acta Paediatr Jpn, Oct. 1994, 36(5), 562-571.
Miller et al., Enteral Feeding of Premature . . . , Arch Dis Child, Nov. 1993, 69 (5 Spec No), 483-487.
Link-Amster et al., Modulation of a Specific . . . , FEMS Immunol Med Microbiol, Nov. 1994, 10 (1), 55-63.
Bernet et al., Lactobacillus acidophilus . . . , Gut, Apr. 1994, 35 (4), 483-489.
Hillman et al., The Effect of Mixtures . . . , Lett Appl Microbiol, Feb. 1995, 20 (2), 130-133.
Greene et al., Factors Involved in Adherence . . . , Appl Environ Microbiol, Dec. 1994, 60 (12), 4487-4494.
Bomba et al., Colonization of the Digestive . . . , Vet Med (Praha), 1994, 39 (11), 701-710.
Bomba et al., Interactions of Lactobacillus . . . , Vet Med (Praha), May 1996, 41 (5), 155-158.
Gewolb Ira H.
Morris, Jr. J. Glenn
Panigrahi Pinaki
Creighton Wray James
Naff David M.
Narasimhan Meera P.
ProBiotix, Inc.
Ware Deborah K.
LandOfFree
Preventing/treating neonatal NEC by administering lactobacillus does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Preventing/treating neonatal NEC by administering lactobacillus , we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Preventing/treating neonatal NEC by administering lactobacillus will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-465664