Preventing renal failure employing nicotinic acid

Details Preventing renal failure employing nicotinic acid Preventing renal failure employing nicotinic acid

1980-12-04

1984-09-18

Robinson, Allen J.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Parasitic organism or component thereof or substance...

A61K 31455

Patent

active

044724101

ABSTRACT:
A method and substances are featured for reducing the risk of incurring renal damage or failure. Substances useful in the treatment of hyperlipidemia and closely-related vascular conditions have been found to reduce or prevent renal failure. The substances most generally utilized are derivatives of phenoxyacetic acid. These substances are administered from 0.01 to 0.25% by weight of the dietary materials ingested by the host which is equivalent to 0.2 to 6.0 grams per day in man.

REFERENCES:
Edwards et al.; Med. J. Aust. (1972) 2, p. 167.
Edwards et al.; Lancet, (1973) 1, p. 1192.
Ibels et al.; British Med. Journal, pp. 552-554 (1976).
Issekutz; Canadian Journal of Physiology+Pharmocology, vol. 49 (1971), pp. 102-105.
Edwards et al.; Aust. NZJ. Med. 4:420 (1976).
Edwards, Artery; 3(2) 135-149 (1977).
Issekutz; C.A. vol. 74 (1971) 110013s.

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