Preventing renal failure

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Recombinant or stably-transformed bacterium encoding one or...

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424127, 424236, 424266, 424267, 424274, 424317, 424319, 424329, 424337, A61K 3119, A61K 31195, A61K 31235, A61K 31455

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042501911

ABSTRACT:
A method and substances are featured for reducing the risk of incurring renal damage or failure. Substances useful in the treatment of hyperlipidemia and closely-related vascular conditions have been found to reduce or prevent renal failure. The substances most generally utilized are derivatives of phenoxyacetic acid. These substances are administered from 0.01 to 0.25% by weight of the dietary materials ingested by the host which is equivalent to 0.2 to 6.0 grams per day in man.

REFERENCES:
patent: 3262850 (1966-07-01), Jones et al.
patent: 3517050 (1970-06-01), Bolhofer
Schapel et al.; In Drugs & The Kidney, Edwards, K. D. G., _Ed. Progr. Biochem, Pharmacol., vol. 9, pp. 82-98, Karger, Basel 1974.
Edwards; In Drugs Affecting Kidney Function & Metabolism, _Edwards, K. D. G., Ed. Progr. Biochem. Pharmacol., vol. 7, pp. 370-426, Karger, Basel 1972.
Schapel et al., J. Pharmacol. Exper. ther. 194:274-284, (1975).
Edwards, Artery 3(2):135-149, Apr. 1977.
Med. Journal of Australia, 2:115-118, 1974.

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