Preventing opiate tolerance by cellular implantation

Drug – bio-affecting and body treating compositions – Whole live micro-organism – cell – or virus containing – Animal or plant cell

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Details

604 49, 4352402, 424563, A61K 3555, C12N 506

Patent

active

057629250

ABSTRACT:
The use of CNS transplants, in particular adrenal medullary transplants, in reducing and/or preventing tolerance to opiates.

REFERENCES:
patent: 4753635 (1988-06-01), Sagen
patent: 4980174 (1990-12-01), Sagen
patent: 5550050 (1996-08-01), Holland et al.
Guststein et al., Brain Research 680(1-2): 173-179 (1995).
Miglecz et al., Psychopharmacology 62(1): 29-34 (Mar. 29, 1979).

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