Prevascularized constructs for implantation to provide blood...

Chemistry: molecular biology and microbiology – Differentiated tissue or organ other than blood – per se – or...

Reexamination Certificate

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Details

C424S093100, C435S325000, C435S395000

Reexamination Certificate

active

07052829

ABSTRACT:
This application discloses methods and materials for preparing functional microvascular beds in the laboratory. These prevascularized constructs can be used to vascularize engineered tissue constructs or to revascularize damaged or diseased tissues or organs following implantation. The prevascularized constructs may also deliver genetically engineered gene products to the bloodstream.

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Soker et al, World J Urol 2000;18:10-8.
Carter et al, Surgery 1996;120:1089-94.
Nakano et al, Eur Surg Res 1999;31:240-8.
Bouhadir et al , J Drug Target. 2001;9:397-406.
Eschenhagen et al, FASEB J 1997;11:683-94.

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