Pressurized solvent-free drug aerosol compositions containing hy

Details Pressurized solvent-free drug aerosol compositions containing hy Pressurized solvent-free drug aerosol compositions containing hy

1997-07-14

1998-12-08

Bawa, Raj

Drug, bio-affecting and body treating compositions

Effervescent or pressurized fluid containing

Organic pressurized fluid

424 46, 514937, 514975, A61K 912

Patent

active

058465219

ABSTRACT:
Pressurised aerosol compositions comprise a medicament, a hydrofluorocarbon propellant and a polyethoxylated surfactant, the compositions containing substantially no solvent, other than the propellant, capable of increasing the solubility of the surfactant in the propellant. The compositions according to the invention are advantageous in that the solubility of the surfactant is such as to ensure good dispersion of the medicament and smooth operation of the aerosol valve.

REFERENCES:
patent: 4174295 (1979-11-01), Bargigia et al.
patent: 4810488 (1989-03-01), Jinks
patent: 5225183 (1993-07-01), Purewal et al.
patent: 5605674 (1997-02-01), Purewal et al.
patent: 5653962 (1997-08-01), Akehurst et al.
patent: 5658549 (1997-08-01), Akehurst et al.

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