Chemical apparatus and process disinfecting – deodorizing – preser – Analyzer – structured indicator – or manipulative laboratory... – Means for analyzing liquid or solid sample
Patent
1988-10-13
1991-10-15
Fisher, Richard V.
Chemical apparatus and process disinfecting, deodorizing, preser
Analyzer, structured indicator, or manipulative laboratory...
Means for analyzing liquid or solid sample
436172, G01N 2100
Patent
active
050572792
ABSTRACT:
A fiber optic based chemical sensor detects chemical species in solution. A fluorogenic indicator is forced through an ultrafiltration membrane into an analyte solution. Complex formation between indicator molecules and target ions occurs at the membrane-solution interface where light from a bifurcated fiber optic cable stimulates fluorescence. Fluorescent emission from a sample is transmitted back up the fiber optic cable to a linear photo diode detector. The sensor responds linearly to increasing and decreasing concentration changes on time scales of one second. Chemical modification of an indicator solution enhanced sensitivity.
REFERENCES:
patent: 4344438 (1982-08-01), Schultz
patent: 4390343 (1983-06-01), Walter
patent: 4488814 (1984-12-01), Johnson
patent: 4540280 (1985-09-01), Anderson et al.
patent: 4555936 (1985-12-01), Scott
patent: 4561779 (1985-12-01), Nagamune et al.
patent: 4622974 (1986-11-01), Coleman et al.
patent: 4637729 (1987-01-01), Schoch
patent: 4668619 (1987-05-01), Greenquist et al.
patent: 4710623 (1987-12-01), Lipson et al.
patent: 4716121 (1987-12-01), Block et al.
patent: 4756884 (1988-07-01), Hillman et al.
patent: 4851195 (1989-07-01), Matthews et al.
patent: 4900933 (1990-02-01), Nestor et al.
Miller, "Factors Affecting the Performance of Fiber Optic Probes", Proceegs of the Simposium on Chemical Sensors, 1987, pp. 449-455.
Peterson, John I. et al., "Fiber Optic pH Probe for Physiological Use", Aug. 1964-Aug. 1969, Analytical Chemistry, May 1980.
Jordan, David M. et al., "Physiological pH Fiber-Optic Chemical Sensor Based on Energy Transfer", Analytical Chemistry, 59, 1987, pp. 437-439.
Vurek, G. G., "A Fiber Optic PCO.sub.2 Sensor", Annals of Biomedical Engineering, 2, 1983, pp. 499-510.
Peterson, J. I. et al., "Fiber-Optic Probe for In Vivo Measurement of Oxygen Partial Pressure", Analytical Chemistry, 1984, pp. 62-67.
Zhujun, Zhang, "A Fluorescent Sensor for Aluminum (III), Magnesium (II), Zing (II) and Cadmium (II) Based on Electrostatically Immobilized Quinolin-8-OL Sulfonate", 0003-2670/85, Elsevier Science Publishers B.V., 1985.
Saari, Linda A. et al., "Immobilized Morin as Fluorescence Sensor for Determination of Aluminum (III)", Analytic Chemistry, 55, 1983, pp. 667-670.
Seitz, W. Rudolf, "Chemical Sensors Based on Fiber Optics", Analytical Chemistry, 56, 1, Jan. 1984, pp. 16-24, 33, 34.
Zhujun et al., "Optical Sensor for Sodium Based on Ion-Pair Extraction and Fluorescence", Analytica Chemica Acta, 184, 1986, pp. 251-258.
Nelsen, Lita L., "Ultrafiltration in Plasma Fractionation", Pharmaceutical Technology, May 1979, pp. 51-56.
Miller, Richard M., "Factors Affecting the Performance of Fiber Optic Probes", Proceedings of the Symposium on Chemical Sensors, Dennis R. Turner, Editor, 1987.
Hiraki, Keizo et al., "Simultaneous Determinations of Metal 5-Sulfol-8-Quinolinolates by Differences in Their Fluorescence Lifetimes", Analytica Chemica Acta, 97, 1978, pp. 121-128.
Inman Scott M.
Lieberman Stephen H.
Stromvall Erik J.
Bruckner John J.
Fendelman Harvey
Fisher Richard V.
Keough Thomas Glenn
The United States of America as represented by the Secretary of
LandOfFree
Pressurized membrane chemical sensor does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Pressurized membrane chemical sensor, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Pressurized membrane chemical sensor will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-989453