Pressurized fluorination of hydroxy alkyl groups

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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540544, 540612, 544106, 544238, 544242, 544358, 544404, 546275, 548215, 548229, 548579, C07D26310

Patent

active

048763527

ABSTRACT:
There is disclosed a high yielding process for converting a hydroxy alkyl oxazolidine compound to the corresponding fluoro derivative by reacting the hydroxy compound with .alpha., .alpha.-difluoroalkylamine under pressure.

REFERENCES:
patent: 3153644 (1964-10-01), Ayer
patent: 3169133 (1965-02-01), Ayer
patent: 4235892 (1980-11-01), Nagabhushan et al.
patent: 4311857 (1982-01-01), Nagabhushan et al.
patent: 4435415 (1984-03-01), Bourgery et al.
patent: 4603422 (1986-07-01), Fletcher

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