Pressure sensitive adhesive matrix patches for transdermal deliv

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Web – sheet or filament bases; compositions of bandages; or...

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424447, 424448, A61L 1516

Patent

active

059853174

ABSTRACT:
A method of transdermally or transmucosally delivering a hydrophilic salt form of a drug with a water-based pressure sensitive hydrophobic adhesive matrix patch optionally containing a permeation enhancer is disclosed. A matrix patch comprising a water-based pressure sensitive hydrophobic adhesive, a hydrophilic salt form of a drug, and optionally a permeation enhancer for transdermal or transmucosal delivery of the hydrophilic salt form of the drug is also disclosed.

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R. J. Scheuplein, Permeability of the Skin, 51, Physiological Reviews, 702-47 (1972).

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