Surgery – Container for blood or body treating material – or means used... – Having hollow needle or spike for piercing container or...
Patent
1985-01-17
1987-06-16
Pellegrino, Stephen C.
Surgery
Container for blood or body treating material, or means used...
Having hollow needle or spike for piercing container or...
604415, A61B 1900, A61M 532
Patent
active
046734040
DESCRIPTION:
BRIEF SUMMARY
TECHNICAL FIELD
The present invention refers to a device for ventilating and pressure balancing the interior of a sealed vessel containing a substance which is to be taken out from said vessel e.g. by an injection syringe, said vessel being provided with a closure means comprising a sealing member through which a puncturing member, e.g. a needle can be passed for entering the interior of said vessel.
BACKGROUND OF THE INVENTION
Drugs and medicines of different kinds which are to be injected into a patient are usually delivered in vials sealed by a membrane or sealing plug which can be penetrated by the needle of an injection syringe. The substances are in some cases delivered as solutions and in other cases as dry substances, which firstly have to be dissolved in a solvent, e.g. water, which is injected into the vial by an injection springe. In both cases there are pressure balancing problems when pressing liquid into or taking liquid out from the air-tightly sealed vial.
THE OBJECT OF THE INVENTION AND ITS MOST IMPORTANT FEATURES
The object of the present invention is to provide a pressure balancing system especially intended for vials containing toxic substances, such as cytoxic drugs, etc., which are not allowed to contaminate the ambient air. This has according to the invention been achieved by the fact that said closure means or a connection means attachable onto said vessel is provided with ventilating means arranged to provide a communication between the interior of the vessel and a closed container or alternatively the atmosphere via a filter.
BRIEF DESCRIPTION OF THE DRAWINGS
FIG. 1 is a longitudinal section of a closure means to a vial according to the present invention,
FIG. is a section according to the line II--II in FIG. 3,
FIGS. 3-5 is a longitudinal sections through three other embodiments.
DESCRIPTION OF SOME EMBODIMENTS
Referring to the drawings the numeral 1 denotes a vial sealed by a stopper 2. A connection means 3 is attached to the bottle-neck of the vial 1. The connection means 3 has a bayonet coupling 4 for receiving a transferring member (not shown) of the kind disclosed in the Swedish patent application No. 8301176-7 and International patent application No. PCT/SE84/00075 and for transferring the content of the vial to an injection syringe without any contamination risk. A sealing member 5, e.g. of Teflon R, which can be penetrated by a needle is provided in the connection means 3, which further is provided with a hood 6 extending radially a considerably distance outside the bottle-neck of the vial 1. A torus-shaped expandable balloon 7 is placed under the hood 6 and attached to a cylindrical balloon attachment 8 provided with a liquid-rejecting filter 9. The balloon 7 communicates with the interior of the vial 1 via a hollow needle 10 passed through the stopper 2. The balloon attachment 8 could of course be angled at which angling of the balloon 7 is avoided.
The balloon 7 works as a pressure equalizer when handling the contents of the vial 1. In case the vial 1 contains a dry substance this must firstly be dissolved in a solvent, e.g. water, which is injected with an injection syringe. This will create an overpressure in the vial 1 and the surplus air is then pressed into the balloon 7. On sucking up the dissolved substance into the injection syringe air is sucked back into the vial from the balloon and a negative pressure is avoided. A completely closed pressure equaliztion system has thus been achieved.
In inflated condition the walls of the balloon 7 are stretched and they exert a counter-pressure on the volume of air contained therein.
According to the embodiment shown in FIG. 3 the connection means 3 is provided with a pointed member 11 passed through the stopper 2 of the vial 1. The pointed member 10 is provided with two passages 12 and 13, one 12 for a needle (not shown) for transferring the substance contained in the vial to an injection syringe and the other 13 for ventilating the vial 1. The ventilating passage 13 communicates with a free space 14 between
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Pellegrino Stephen C.
Smith, Jr. Jerome R.
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