Preserving agent and method of use thereof

Details Preserving agent and method of use thereof Preserving agent and method of use thereof

1985-04-15

1987-01-13

Lacey, David L.

Chemistry: analytical and immunological testing

Food or dairy products

Dairy product

436176, 568701, 568713, 426532, 426654, G01N 3304

Patent

active

046364765

ABSTRACT:
A tablet for use in preserving samples of milk for analysis comprises bronopol (2-bromo-2-nitropropane-1,3-diol) and a water-soluble solid organic carboxylic acid, the amount of the organic acid being within the range 0.002-0.07 milli-equivalents per milligram of bronopol. The presence of the organic acid stabilizes the bronopol, thereby providing a tablet with an adequate shelf life. Suitable organic acids include citric acid, tartaric acid, malic acid, adipic acid, succinic acid and fumaric acid.

REFERENCES:
patent: 2282799 (1942-05-01), Musher
patent: 3558788 (1971-01-01), Clark et al.
patent: 3637772 (1972-01-01), Klaui et al.
patent: 4148891 (1979-04-01), Smink
Chem. Abstracts, vol. 93, No. 17, 27-10-1980, p. 206, No. 162713g, Columbus, Ohio, US: and JP -A- 80 73 603 (Green Cross Corp.) 03-06-1980.
Milchwissenschaft, vol. 36, No. 2 (1981), pp. 65-68, J. Thomasow et al.: "Bestimmung des Fett-, Eiweiss- und Milchzuckergehaltes von Milch durch Messung der Infraroabsorption mit dem Gerat Multispec", p. 67, col. 1,2.
WO-A-8 200 056 (Bechman Instruments), Example 1.
US-A-4 258 056 (S. Lentsch), Examples 1-5.
Chem. Abstracts, vol. 96, No 9, Mar. 1, 1982, p. 373, No. 74580t, Columbus, Ohio, US; K. Moore: "The Effect of pH, Temperature and Certain Media Constituents on the Stability and Activity of the Preservative, Bronopol.", & J. Appl. Bacteriol. 1981, 51(3), 483-94.
Croshaw et al., J. Pharm. Pharmacol., vol. 16, 1964, Suppl. pp. 127-130T.
Sykes & Smart, American Perfumer & Cosmetics, vol. 84, 1969, pp. 45-49.
Bronopol Technical Bulletin, Jan. 1977, The Boots Company Ltd.
Bryce & Smart, J. Soc. Cosmetic Chemists, vol. 16, 1965, pp. 187-201.

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