Preserved, non-infectious control cells prepared by the modulati

Details Preserved, non-infectious control cells prepared by the modulati Preserved, non-infectious control cells prepared by the modulati

1996-07-29

1999-01-19

Saucier, Sandra E.

Chemistry: molecular biology and microbiology

Animal cell, per se ; composition thereof; process of...

424534, 436 10, 435 2, 435 721, 435 29, C12N 500, G01N 33567, G01N 3100

Patent

active

058613110

ABSTRACT:
The invention describes the preparation of preserved, non-infectious control cells. The control cells are prepared by modification, activation or otherwise changing selected normal leukocyte cells, tissue culture cells or zenogenic transplants in immunosuppressed animals to have characteristics of abnormal cells or by the addition of cells from an established cell line, which has been similarly modified or activated, to a normal leukocyte population. The preferred method of preserving the control cells is by lyophilization using an isotonic 10% trehalose solution.

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