Preserved hair and body treatment compositions and use of a pres

Details Preserved hair and body treatment compositions and use of a pres Preserved hair and body treatment compositions and use of a pres

1990-05-17

1992-03-31

Page, Thurman K.

Drug, bio-affecting and body treating compositions

Live hair or scalp treating compositions

Amphoteric or zwitterionic surfactant containing

424 47, 424404, A61K 7075

Patent

active

051006561

DESCRIPTION:

BRIEF SUMMARY
BACKGROUND OF THE INVENTION

The present invention relates to an improved method of preserving hair and body treatment compositions and preserved hair and body treatment compositions.
Hair and body treatment compositions generally contain a preservative which is supposed to effectively protect the composition from infection by microorganisms.
Conflicting demands are made on a preservative for use in hair and body treatment compositions. Thus, on the one hand, it should be favorably tolerated in physiological and dermatological respects and, on the other hand, should possess a good germ inhibiting or even germ killing action. These two demands are usually very difficult to reconcile.
The usual preservatives used in hair and body treatment compositions are e.g. formaldehyde (a), 5-bromo-5-nitro-1,3-dioxane (b), p-hydroxybenzoic acid ester (c), 2,4,4,-trichloro-2,-hydroxydiphenylether (d), 5-chloro-2-methyl-3-isothiazolone (e), 2-methyl-3-isothiazolone (f), and 2-bromo-2-nitropropane-1,3-diol (g).
Recently, some preservatives, such as formaldehyde and 2-methyl-3-isothiazolone, have been suspected of not being sufficiently tolerated. It is known with respect to aldehydes and phenols having a preservative action that they react with proteins or interact with them in a denaturating manner. In addition, there is the risk of sensitization with aldehydes.
Another risk of using such preservatives is the danger of nitrosamine formation. In raw materials containing nitro groups ((b)+(g)), this risk is particularly high when they are used together with other nitrogen-containing components of the cosmetic composition.
Preservatives which do not have the aforementioned disadvantages have already been suggested.
For example, a hair and body cleansing composition is described in DE-OS 3 644 473 which contains a physiologically tolerated salt of formic acid, salicylic acid or its salt, and a physiologically unobjectionable organic or inorganic acid.
However, the use of salicylic acid as preservative is not completely satisfactory, since the salicylic acid can lead to skin rashes with very sensitive people or in exceptional cases to asthma attacks. Moreover, they have a keratolytic effect when used in higher concentrations, which means that they can dissolve the callous layer of the skin.


SUMMARY OF THE INVENTION

Therefore, it is an object of the present invention to provide a hair and body treatment composition containing a combination of preservatives which has a good preservative action, is better tolerated physiologically than the usual preservatives used in such compositions, and which avoids the disadvantages of salicylic acid mentioned above.
It has been found that an aqueous hair and body treatment composition with a content of 0.1 to 50 percent by weight of a surfactant or a surfactant mixture characterized in that it contains a combination of organic acids,
Sorbic acid is found in nature in the rowanberry (Sorbus aucuparia).
The composition, according to the invention, is better preserved by means of the combination of preservatives described above than the hair and body cleansing composition containing salicylic acid described in DE-OS 3 644 473.
For this reason, the applied concentration of the new preservative system comprising components (A)-(C) can be clearly lower than in the case of DE-OS 3 644 473, so that a better compatibility is achieved simultaneously.
Whereas e.g. a hair and body treatment composition, according to DE-OS 3 644 473, which contains 0.05 percent by weight sodium formate and 0.05 percent by weight salicylic acid is no longer sufficiently preserved, the same composition preserved with 0.05 percent by weight sodium formate and 0.05 percent by weight sorbic acid surpasses the demands of the preservative test.
This is particularly surprising because sorbic acid alone, in low concentrations, does not sufficiently preserve cosmetic compositions, but is irritating to the skin in higher concentrations, e.g. according to H. Janistyn, Handbook of Cosmetics and Scents [Handbuch der Kosmetika und R

REFERENCES:
patent: 4971784 (1990-11-01), Holzel et al.
Remington's Pharmaceutical Sciences Treatise 1990 Mack Publishing Co. p. 1288.

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