Preservative system for topically applied products

Details Preservative system for topically applied products Preservative system for topically applied products

1998-07-16

2000-09-19

Clardy, S. Mark

Drug, bio-affecting and body treating compositions

Topical body preparation containing solid synthetic organic...

424401, 424404, 514844, 514887, 514938, A61K 3174

Patent

active

061207586

ABSTRACT:
A preservative system for topically applied products includes one or more of benzyl alcohol, disodium EDTA, and a para-hydrobenzoic acid, in an effective antimicrobial amount, combined with one or more enhancers selected from the group of sorbic acid, salts of sorbic acid, benzoic acid, salts of benzoic acid, and a phospholipid. This preservative system has been found to effectively prevent the growth of bacteria, yeast and mold, without irritation of the skin as occurs with many prior preservatives. The preservative system is therefore ideal for incorporation into topical preparations such as cosmetics, skin care products, and pharmaceutical compositions (such as dermatologic, otic and ophthalmic preparations).

REFERENCES:
patent: 5683683 (1997-11-01), Scafidi

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