Preservation of blood platelets with citrate

Chemistry: molecular biology and microbiology – Maintaining blood or sperm in a physiologically active state...

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

Reexamination Certificate

active

07083910

ABSTRACT:
Methods and compositions for preserving blood platelet suspensions which can be stored and preserved for extended periods of time are provided herein. The methods and compositions employ a mixture comprising blood platelets and one or more citrate salts. Such blood platelet mixtures may be cooled either rapidly or slowly and stored for several days prior to use in patients.

REFERENCES:
patent: 4059967 (1977-11-01), Rowe et al.
patent: 5376524 (1994-12-01), Murphy et al.
patent: 5496821 (1996-03-01), Arduino
patent: 5753428 (1998-05-01), Yuasa et al.
patent: 6613566 (2003-09-01), Kandler et al.
patent: 2003/0158507 (2003-08-01), Serebrennikov et al.
patent: 2929278 (1981-01-01), None
patent: 54-103184 (1979-08-01), None
patent: 04001135 (1992-01-01), None
patent: WO 91/17655 (1991-11-01), None
patent: WO00/53008 (2000-09-01), None
patent: WO03/000052 (2003-01-01), None
Young et al., “Reduction in Potassium Concentration Increases Platelet Sensitivity to Thrombin and ADP”, FASEB Journal 6 (4): A1598 (1992).
Leven et al., “Effects of Altered pH and Sodium Concentration on the Response of Megakaryocytes and Platelets to ADP”, Thrombosis and Haemostasis 46 (1): 70 (981).
Hernandez-Hernandez et al., Loss of phosphotyrosine phosphatase activity and changes in the tyrosine phosphorylation state of proteins after storage of sheep platelets in plasma or Seto solution at 4*C. Vox Sanguis 81 : 241-47 (2001).
Database WPI: Section CH, Week 198524 Derwent Publication Ltd., London, AN 1985-144847, SU1124974A (As Sibe Biophys).
Brodthagen, U.A. et al. “Platelet cryopreservation with glycerol, dextran, and mannitol: Recovery of 5-hydroxytryptamine uptake and hypotonic stress response.”Cryobiology(1985) vol. 22(1): Abstract only.
Smillie, J.A. et al. “Cryopreservation of human platelets with polyvinylpyrrolidone.”Transfusion(1981) vol. 21(5): Abstract only.
Sputtek, A. et al. “Cryopreservation of human platelets with hydroxyethyl starch in a one-step procedure.”Cryo-Letters(1987) vol. 8(4): 218-231.
Odink, J. et al. “Platelet preservation part 1. The use of decrease in light absorbance as a screening method in cryopreservation studies on human platelets.”Cryobiology(1977) vol. 14(5): 519-528.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Preservation of blood platelets with citrate does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Preservation of blood platelets with citrate, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Preservation of blood platelets with citrate will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-3651682

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.