Chemistry: analytical and immunological testing – Composition for standardization – calibration – simulation,... – Preservative – buffer – anticoagulant or diluent
Patent
1994-07-22
1996-11-19
Housel, James C.
Chemistry: analytical and immunological testing
Composition for standardization, calibration, simulation,...
Preservative, buffer, anticoagulant or diluent
436 8, 435 2, 424532, G01N 3349
Patent
active
055762131
ABSTRACT:
Methods and compositions for preserving platelets at cryogenic temperatures with retention of hemostatic activity are provided. The compositions include a first agent for inhibiting actin filament severing and a second agent for inhibiting actin polymerization. Contacting the platelets with the first and second agents prior to exposure to cold temperature prevents cold-induced platelet activation.
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Hartwig John H.
Janmey Paul A.
Stossel Thomas P.
Brigham & Women's Hospital Inc.
Freed Rachel Heather
Housel James C.
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