Chemistry: molecular biology and microbiology – Maintaining blood or sperm in a physiologically active state...
Patent
1993-02-18
1994-10-25
Housel, James C.
Chemistry: molecular biology and microbiology
Maintaining blood or sperm in a physiologically active state...
436 8, 514 2, 424532, A01N 102
Patent
active
053588444
ABSTRACT:
Methods for preserving platelets at temperatures of less than about 15.degree.C. with retention of hemostatic activity are provided. The method uses a first agent for inhibiting actin filament severing and a second agent for inhibiting actin polymerization. Contacting the platelets with the first and second agents prior to exposure to cold temperature prevents cold-induced platelet activation.
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Hartwig John H.
Janmey Paul A.
Stossel Thomas P.
Brigham and Women's Hospital, Inc.
Housel James C.
Tran Lien
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