Pres2+S hepatitis B vaccine derived from plasma

Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Separation or purification

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530412, 530415, 530418, 530422, 530402, 530403, 530405, 530406, 530427, 530827, 530830, 530380, 424 89, C07K 328, C07K 318

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active

050307207

ABSTRACT:
Hepatitis B PreS2+S antigen is isolated from plasma by adsorption on an affinity chromatography column, elution with a chaotropic agent and treatment with concentrated urea at an elevated temperature. The process retains all or substantially all of the preS2+S antigen.

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