Preparing a reactor containing enzymes attached to dialdehyde ce

Textiles: fiber preparation

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195 31R, 195 63, 195DIG11, 426 12, C07G 702

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active

040135144

ABSTRACT:
Water-insoluble, biologically active conjugates for use in a reactor core of a flow-through reactor are prepared by covalently bonding an enzyme directly to a fibrous dialdehyde cellulose such as cotton. Preferably the fibrous cellulose is placed in the reactor core of a flow-through reactor before or after it is treated with periodic acid solution to convert glucose units thereof to units containing dialdehyde groups. Thereafter, an enzyme solution is passed through the resultant dialdehyde cellulose to bind the enzyme to the cellulose.

REFERENCES:
patent: 3705084 (1972-12-01), Reynolds
patent: 3706633 (1972-12-01), Katchalski et al.
patent: 3753861 (1973-08-01), Forgione
Weliky et al., The Chemistry and Use of Cellulose Derivatives for the Study of Biological Systems, Immunochemistry, Vol. 2, 1965, (pp. 293-305).

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