Preparations of purified bacterial membranal proteoglycans

Drug – bio-affecting and body treating compositions – Whole live micro-organism – cell – or virus containing – Genetically modified micro-organism – cell – or virus

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260112R, 424 88, A61K 3900, A61K 39102, A61K 3909, C07G 700

Patent

active

043978380

ABSTRACT:
This invention relates to a process for the preparation of purified bacterial membranal proteoglycans. The process comprises at least one step in which crude proteoglycans are treated in aqueous medium with a base or a hypobromite, followed by elimination of the excess reactant and the insoluble residue, the purified proteoglycans being present in aqueous solution. The thus obtained purified proteoglycans may be used as immunity adjuvants in vaccines without causing side-effects such as pyrogenic reactions.

REFERENCES:
patent: 3855197 (1974-12-01), Hirsch et al.
patent: 4036953 (1977-07-01), Adam et al.
patent: 4042678 (1977-08-01), Corbaru et al.
patent: 4069314 (1978-01-01), Adlam et al.
patent: 4094971 (1978-06-01), Chedid et al.

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