Preparations containing 2-bromo- and 2-nitroxy derivatives of 3-

Details Preparations containing 2-bromo- and 2-nitroxy derivatives of 3- Preparations containing 2-bromo- and 2-nitroxy derivatives of 3-

1995-07-10

1997-06-10

Spivack, Phyllis G.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

A61K 31395

Patent

active

056375816

ABSTRACT:
Formulations exhibiting antibacterial inhibitory or antitumor action containing an effective amount of 2-bromo-and 2-nitroxy derivatives of 3-bromo and 3,3-dibromo-4-oxo-azetidine, and a method of use of the formulations are provided.

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Wolfe et al., Sulfur-free Penicillin Derivatives.III.Regeneration of Fused .beta.-Lactams via Intramolecular Displacement, Can. J. Chem., (1972), vol. 50, pp. 2902-2905.
Sheehan et al., Removal and Displacement of the Thiazolidine Ring in Penicillin. II..sup.1 Selective Carbon-Sulfur Bond Cleavage, Jour. Am. Chem. Soc., (1973), vol. 95, No. 9, pp. 3064-3065.
Kukolja, Electrophilic Opening of the Thiazolidine Ring in Penicillins, Jour. Am. Chem. Soc., (1971), vol. 93, No. 23, pp. 6267-6269.
Kukolja, A Stereoselective Synthesis of 6-Phthalimido-5-epipenicillanates, Jour. Am. Chem. Soc., (1971), vol. 93, No. 23, pp. 6269-6270.

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