Preparation process of indoles

Details Preparation process of indoles Preparation process of indoles

1990-11-06

1992-12-29

Brust, Joseph Paul

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

548469, 548489, C07D20930, C07D20904

Patent

active

051753081

ABSTRACT:
A process is provided for the preparation of an indole from aniline or a derivative thereof and a polyhydric alcohol. The reaction is carried out in the presence of a catalyst composed of a carrier having a specific surface area of at least 10 m.sup.2 /g and silver supported on the carrier. The catalyst also contains as an additional component a specific amount of at least one element selected from Co, Fe and Ni. Deterioration in catalytic performance of the catalyst during the reaction and its regeneration are therefore minimized.

REFERENCES:
patent: 4476310 (1984-10-01), Honda et al.
patent: 4831158 (1989-05-01), Ueno et al.
patent: 4937353 (1990-06-01), Kudoh et al.

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