Preparation process of acemetacin

Details Preparation process of acemetacin Preparation process of acemetacin

1984-04-11

1986-07-29

Hollrah, Glennon H.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C07D20928

Patent

active

046032100

ABSTRACT:
A process for preparing acemetacin which process comprises removing a protecting group, which is other than tetrahydropyranyl group and is removable under acidic conditions, from an acemetacin ester represented by the formula ##STR1## wherein R means the protecting group, under the acidic conditions.

REFERENCES:
patent: 3483220 (1969-12-01), Gaines et al.
patent: 4104278 (1978-08-01), Boltze et al.
patent: 4165428 (1979-08-01), Noda et al.
patent: 4181740 (1980-01-01), Zumin et al.
Boltze, Drug Res., 30 (II), pp. 1314 et seq. (1980).

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