Preparation process of 2-hydroxy-3-alkoxypropylglyceryl ether

Organic compounds -- part of the class 532-570 series – Organic compounds – Oxygen containing

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549453, 568623, C07C 4311, C07D31700

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active

044658664

ABSTRACT:
Some 4-(2'-hydroxy-3'-alkoxy)propoxymethyl-1,3-dioxolanes are prepared by reacting alkylglycidyl ethers with acetal or ketal derivatives of glycerol in the presence of an acidic or basic catalyst. Also disclosed is a process for preparing certain 2-hydroxy-3-alkoxy-propylglyceryl ethers, which process comprises subjecting the 4-(2'-hydroxy-3'-alkoxy)propoxymethyl-1,3-dioxolanes to hydrolysis. The above processes can afford intended reaction products with good yield without need for any special post-reaction treatment.

REFERENCES:
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patent: 3201420 (1965-08-01), Fuzeu et al.
patent: 3651090 (1972-03-01), Hardie et al.
patent: 4298764 (1981-11-01), Berkowitz
H. Meerwein: Houben-Weyl, Methods of Organic Chemistry, vol. 6/3, pp. 40-43.

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