Preparation of water soluble cellulose acetate microspheres

Plastic and nonmetallic article shaping or treating: processes – Formation of solid particulate material directly from molten...

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264 43, 264 46, 424461, 424488, 424499, 4284022, 512 4, 514963, B29B 900, B29B 912

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049975994

ABSTRACT:
Microparticle of cellulose acetate and derivatives thereof characterized by being water soluble, having a large interior void space and having a plurality of open exterior surface pores. These water soluble microparticles can be loaded with a chemical selected from the group consisting of pharmaceuticals, dyes, flavorings, agriculturals, solid catalysts and fragrances. The microparticles are produced by forming spherical droplets of a dope of water soluble cellulose acetate and water soluble derivatives of cellulose acetate with a solvent therefor, precipitating the spherical droplets in a bath of a precipitant for water soluble cellulose acetate and water soluble derivatives of cellulose acetate, separating the excess precipitant from the microparticles, enriching the microparticles with the precipitant by contacting the microparticles one or more times with a solution of the precipitant, removing rapidly under vacuum substantially all of the precipitant from the microparticles, and recovering the resulting water soluble microparticles.

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