Preparation of thioarabinofuranosyl compounds and use thereof

Details Preparation of thioarabinofuranosyl compounds and use thereof Preparation of thioarabinofuranosyl compounds and use thereof

2005-03-22

2005-03-22

Raymond, Richard L. (Department: 1624)

Organic compounds -- part of the class 532-570 series

Organic compounds

Four or more ring nitrogens in the bicyclo ring system

C544S182000, C544S317000

Reexamination Certificate

active

06870052

ABSTRACT:
Patients suffering from cancer are treated by being administered a compound represented by the following formula:wherein each R individually is H or an aliphatic or aromatic acyl group;A is selected from the group consisting ofwherein X is selected from the group consisting of hydrogen, fluorine, alkoxy, alkyl, haloalkyl, alkenyl, haloalkenyl, alkynyl, amino, monoalkylamino, dialkylamino, cyano and nitro. The above compounds also inhibit DNA replication in mammalian cells.

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