Organic compounds -- part of the class 532-570 series – Organic compounds – Carboxylic acids and salts thereof
Patent
1978-03-24
1980-02-12
Helfin, Bernard
Organic compounds -- part of the class 532-570 series
Organic compounds
Carboxylic acids and salts thereof
560255, 562460, 562469, 562470, 544176, C07C 6333
Patent
active
041884914
ABSTRACT:
A process is disclosed for preparing arylpropionic acids of formula Ar--CH(CH.sub.3)--COOH, by reacting an aryl Grignard reagent with a metal pyruvate or with a pyruvamide, to form a hydroxy acid of formula Ar--C(OH)(CH.sub.3)--COOH or its amide, and converting the acid or amide to the product.
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Standen, Kirk-Othmer Encyc. Chem. Tech., 2d Ed., 10, Interscience Publ., N.Y., 721-733 (1966).
Nicholson John S.
Turner John L.
Breitenstein G. T.
Helfin Bernard
Hueschen Gordon W.
The Boots Company Limited
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