Preparation of substituted piperidenes

Details Preparation of substituted piperidenes Preparation of substituted piperidenes

1994-07-12

1997-09-02

Kelly, C. H.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

546176, 546185, 546193, 546207, 546208, 546212, 546214, 546264, C07D21512, C07D21504, C07D21102, C07D21168

Patent

active

056633491

ABSTRACT:
Novel processes are disclosed for the preparation and resolution of substituted piperidines of the formula ##STR1## wherein R.sup.1 and R.sup.2 are defined as below, and related compounds, as well as novel intermediates used in such processes.

REFERENCES:
patent: 3560510 (1971-02-01), Warawa et al.
patent: 4358446 (1982-11-01), Haken et al.
patent: 4377691 (1983-03-01), Yasui et al.
patent: 4552960 (1985-11-01), Krumkalns et al.
patent: 4680283 (1987-07-01), Veber et al.
patent: 5138060 (1992-08-01), Godek et al.
patent: 5162339 (1992-11-01), Lowe
Chem. Abs., 91:140686 (1979), Rakhit et al.
Solomons et al., Organic Chemistry (1976).
E. J. Warawa et al. "Quinuclidine Chemistry", J. Med. Chem., 18, 587 (1975).
Sandberg et al. "Substance P," J. Med. Chem., 25, 1009, (1982).
P.J. Goadsby et al. "Release of Vasoactive Peptides" Ann. Neurol., 23, 193 (1988).
Regoli, "Neurokinin Agonists & Antagonists" Elsevier Scientific Publishers, Amsterdam, pp. 85-95 (1987).
L.S. Trifonov et al. "Synthesis of 1,2-Five-Ring-Annellated Barrelenes" Helvetica Chimica Acta, 70, 4, 1732-1736 (1987).
A.S. Yanni et al., "Synthesis & biological Activity" Indian J. Chem., 21B (7), 705-6, (1982).
Y.P. Gupta et al. "Synthesis of 2,12-Diazachrysene via Benzyne Cyclization Reaction," Indian J. Chem., 19B (5), 400-1, (1980).
V.N. Gogte et al. "Infrated Spectral Study of the Effect of Substitution on Conformation and Hydrogen Bonding in 3-(aryl-amino)propanols," Indian J. Chem., 17B (3), 230-2, (1979).
S.V. Kessar et al. "New Routes to Condensed Polynuclear Compounds," Tetrahedron, 29, Pergamon Press, (GB), 419-424, 1978.
G.N. Walker et al. "Synthesis of Caried Heterocyclic & Substituted Arylalkyl" J. Med. Chem., 9, No. 4, (1966), 624-630.
G.N. Walker et al. "Application of Sodium Borohydride" Journal of Organic Chemistry, 26, No. 8, (1961), American Chemical Society, (US), 2740-2747.
Suman Rakhit et al. "Formation of Animals from Amines via Pummerer Rearrangement," Can. J. Chem., 57, No. 10, 1153 (1979).
Webster's Ninth New Collegiate Dictionary, p. 745 (1990).
Morrison et al., Organic Chemistry, pp. 92-93, (3rd Ed., Allyn and Bacon, Inc.) (1973).
Greene et al., Protective Groups in Organic Synthesis, pp. 1-9, 309-317, 349, 350, 362, 363 and 372, (2nd Ed., John Wiley & Sons, Inc.) (1991).

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