Preparation of substituted guanidine derivatives

Details Preparation of substituted guanidine derivatives Preparation of substituted guanidine derivatives

1998-10-27

1999-10-19

McKane, Joseph K.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acids and salts thereof

564241, C07C24902

Patent

active

059691824

ABSTRACT:
Substituted guanidine derivatives of the formula I, ##STR1## are prepared by a) reacting calcium cyanamide with an alcohol of the formula R.sup.10 --OH to give an isourea derivative of the formula II, ##STR2## and b) reacting the substituted isourea with a primary or secondary amine of the formula III, ##STR3## where the substituents R.sup.1 and R.sup.2 and R.sup.10 have the meanings explained in the description.

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Chem. Ber., 33 (1900), pp. 1517-1519.

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