Preparation of substituted amines

Organic compounds -- part of the class 532-570 series – Organic compounds

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564329, 2521881, C07F 502

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active

046706003

ABSTRACT:
Amines are substituted, e.g. alkylated, by reacting the unsubstituted amine with a ketone or aldehyde, a borohydride and a rigid acid.

REFERENCES:
patent: 4071557 (1978-01-01), Mattner
patent: 4083871 (1978-01-01), Houlihan et al.
Gribble et al., J. Amer. Chem. Soc. 96 (25), pp. 7812-7814 (1974).
Gribble et al., Synthesis pp. 650-652 (1975).
Chemical Abstracts 87 184194s (1977).

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