Preparation of substituted alkenoic acids

Details Preparation of substituted alkenoic acids Preparation of substituted alkenoic acids

1997-05-23

1998-12-15

Fan, Jane

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

546194, 544131, C07D41310, A61K 3144

Patent

active

058499229

ABSTRACT:
This invention relates to a highly selective process for preparation of E-.omega.-phenyl-.omega.-(3-pyridyl)-.omega.-alkenoic acid derivatives bearing a carbamoyl substituted oxazolyl or oxazolinyl group on the phenyl ring which demonstrate utility for thromboxane receptor antagonism and/or thromboxane synthase inhibition, as well as to intermediates therefor.

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