Preparation of stroma-free, non-heme protein-free hemoglobin

Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal

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2601125R, 424101, 424177, A61K 3514, A61K 3704, C07C10352

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active

044734948

ABSTRACT:
A method for the production of stroma-free, non-heme protein-free hemoglo by use of zinc ion to promote precipitation of a zinc ion-bound insoluble hemoglobin complex, followed by membrane ultrafiltration of the zinc-hemoglobin complex from the filtrate fluid medium, preferably with a saline dialyzate.

REFERENCES:
patent: 3991181 (1976-11-01), Doczi
patent: 4001401 (1977-01-01), Bonsen et al.
patent: 4376059 (1983-03-01), Davis et al.
J. of Exptl. Med., 126, 1127-1142, (1967), Rabiner et al.
Hemoglobin 6(2), 183-186, (1982), Lehmann et al.

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