Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Hydrocarbon doai
Patent
1991-10-01
1995-09-26
Page, Thurman K.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Hydrocarbon doai
264 41, 424450, 585351, A61K 31015, A61K 3722, B01J 1302, C07C40324
Patent
active
054534470
ABSTRACT:
A process for the continusous preparation of Beta-carotene together with an emulsifier by briefly heating Beta-carotene together with an emulsifier to give a homogeneous solution, rapidly cooling the latter to below 100.degree. C. by adding water, and subsequently adjusting to the required final concentration of Beta-carotene, comprises pumping a suspension, which has been preheated from 20.degree. to 80.degree. C., of 1 to 40% by weight of Beta-carotene in an emulsifier through a heating coil located in a heat transfer oil, where the solubilization mixture is at from 120.degree. to 180.degree. C. and the residence time is from 10 to 300 seconds, and subjecting the homogenous solution to turbulent mixing in a mixing chamber with an amount of water at from 10.degree. to 80.degree. C. to result in a solubilizate which contains from 0.5 to 6% by weight of Beta-carotene and is, if necessary, diluted to the required final concentration.
REFERENCES:
patent: 2976024 (1961-03-01), Martinek
patent: 3932634 (1976-01-01), Kardys
patent: 4075333 (1978-02-01), Josse
patent: 4435427 (1984-03-01), Hoppe et al.
End Lutz
Hoppe Peter P.
Horn Dieter
Lueddecke Erik
Rensmann Friedrich-Wilhelm
Azpuru Carlos
BASF - Aktiengesellschaft
Page Thurman K.
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