Preparation of solid medicament formulation containing nitrendip

Details Preparation of solid medicament formulation containing nitrendip Preparation of solid medicament formulation containing nitrendip

1985-09-05

1988-02-09

Robinson, Allen J.

Drug, bio-affecting and body treating compositions

Lymphokine

514356, A61K 3144, A61K 3179

Patent

active

047241411

ABSTRACT:
A solid medicament formulation comprising 1 part by weight of crystalline nitrendipine, 0.5-1 part by weight of polyvinylpyrrolidone, 0.05-0.5 part by weight of sodium lauryl-sulphate, 1-6 parts by weight of corn starch, 0.5-4 parts by weight of microcrystalline cellulose, 0-5 parts by weight of lactose and 0.01-0.05 parts by weight of magnesium stearate. Such small size formulation has a high bioavailability.

REFERENCES:
patent: 4237137 (1980-12-01), Tacke et al.
patent: 4537898 (1985-08-01), Hoff et al.
patent: 4582840 (1986-04-01), Gerthoff et al.

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