Preparation of salts of pharmaceutical active substances which h

Details Preparation of salts of pharmaceutical active substances which h Preparation of salts of pharmaceutical active substances which h

1997-06-10

1999-10-19

Killos, Paul J.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acids and salts thereof

C07C 5334

Patent

active

059691816

ABSTRACT:
A process for preparing salts of pharmaceutical active substances which have acidic groups by reacting the carboxylic acids with a base in the melt, wherein the acids are reacted with at least the stoichiometric amount of a base in an extruder.

REFERENCES:
patent: 4060535 (1977-11-01), Cinco

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