Preparation of (S)-2-amino-6, 6-dimethoxyhexanoic acid methyl es

Details Preparation of (S)-2-amino-6, 6-dimethoxyhexanoic acid methyl es Preparation of (S)-2-amino-6, 6-dimethoxyhexanoic acid methyl es

1999-07-08

2000-12-26

Owens, Amelia

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

549451, C07D31700

Patent

active

061662275

ABSTRACT:
The glycinamide of the formula (I) ##STR1## is reacted with the dioxolane of the formula (II) ##STR2## wherein L is a leaving group such as iodo, bromo, alkylsulfonyloxy, or arylsulfonyloxy to give the dioxolane of the formula (III) ##STR3## Treatment of (III) gives the dioxolane pentanoic acid IV ##STR4## which can be converted to (S)-2-amino-6,6-dimethoxyhexanoic acid, methyl ester.

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