Preparation of readily disintegrable tablets

Details Preparation of readily disintegrable tablets Preparation of readily disintegrable tablets

1975-04-22

1977-04-12

Rose, Shep K.

Drug, bio-affecting and body treating compositions

Solid synthetic organic polymer as designated organic active...

Polymer from ethylenic monomers only

424362, A61J 310, A61K 4700

Patent

active

040175987

ABSTRACT:
Methylcellulose with or without the addition of medically active ingredients and other additives is first granulated by a known method into granules of appropriate size and then the granules are blended with a disintegrator and compressed into tablets. The tablets obtained by the method have sufficient hardness and very short disintegration time when taken into the human body in comparison with the poor disintegrability of tablets directly shaped from powdery methylcellulose or a methylcellulose-based mixture of active ingredients. The method is useful for tableting some medicinals of poor tabletability, such as, pancreatin which require large amounts of a binder to be successfully shaped into tablets. Tablets of methylcellulose prepared in accordance with the method can find use as a non-caloried food.

REFERENCES:
patent: 2883327 (1959-04-01), Dale
patent: 3065143 (1962-11-01), Christensen et al.
patent: 3079303 (1963-02-01), Raff et al.
patent: 3133863 (1964-05-01), Tansey
patent: 3266992 (1966-08-01), De Jong
patent: 3725556 (1973-04-01), Hanssen
patent: 3852421 (1974-12-01), Koyanagi et al.
patent: 3907983 (1975-09-01), Seth
patent: R27679 (1973-06-01), Bentholm et al.
Khan et al., Chem. Abst. 82, No. 116041M, (1975), Abst. of J. Pharm, Sci. 64(1): 166-168 (1975).
Mendel, Chem. Abst. 82, No. 129227b, (1975), Abst. of Pharm. Acta. Helv. 49(7/8): 248-250 (1974).
Khan et al., Chem. Abst. 82, No. 144889N, (1975), Abst. of J. Pharm. Pharmacol. 26, Suppl. 106p-107p(1974).

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