Preparation of pyrazolo(5,1-B)quinazolones

Details Preparation of pyrazolo(5,1-B)quinazolones Preparation of pyrazolo(5,1-B)quinazolones

1988-09-09

1990-05-15

Schwartz, Richard A.

Organic compounds -- part of the class 532-570 series

Organic compounds

Four or more ring nitrogens in the bicyclo ring system

C07D48704

Patent

active

049259466

ABSTRACT:
Pyrazolo[5,1-b]quinazolones are prepared by reacting isatoic anhydrides with 3-methylpyrazol-5-one in water as reaction medium at from 40.degree. to 150.degree. C. under from 1 to 5 bar.

REFERENCES:
K. Menzel et al., Angew. Chem. vol. 74, pp. 839-847 (1962).
J. Sircar et al., Journal of Heterocyclic Chemistry, vol. 18, 1981, pp. 117-121.
J. Sircar et al., Journal of Medicinal Chemistry, vol. 24, 1981, pp. 735-742.

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