Chemistry: molecular biology and microbiology – Virus or bacteriophage – except for viral vector or... – Recovery or purification
Reexamination Certificate
2007-01-30
2010-10-05
Lucas, Zachariah (Department: 1648)
Chemistry: molecular biology and microbiology
Virus or bacteriophage, except for viral vector or...
Recovery or purification
C435S005000, C435S006120, C435S007100, C536S023720
Reexamination Certificate
active
07807438
ABSTRACT:
The invention relates to a method for isolation of hepatitis C virus. The method comprises the separation of particles termed exosomes from the blood plasma of an individual infected with hepatitis C virus (HCV) and the extraction or RNA from these exosome particles.
REFERENCES:
patent: 5959092 (1999-09-01), Miyamura et al.
patent: 7198923 (2007-04-01), Abrignani et al.
patent: WO 91/15574 (1991-10-01), None
patent: WO 96/05513 (1996-02-01), None
patent: WO 97/05900 (1997-02-01), None
patent: WO 97/09349 (1997-03-01), None
patent: WO 99/18198 (1999-01-01), None
patent: WO 99/24054 (1999-04-01), None
patent: WO 99/03499 (1999-05-01), None
Nagasaka et al., “Differential flotation centrifugation study of hepatitis C virus and response to interferon therapy,” Journal of Medical Virology, vol. 52 No. 2, pp. 190-194 (1997).
Escola, et al., “Selective Enrichment of Tetraspan Proteins on the Internal Vesicles of Multivesicular Endosomes and on Exosomes Secreted by Human B-Lymphocytes,”J. Biol Chem. 273:20121-20127 (1998).
Harding, et al., “Immunogenic Peptides Bind to Class II MHC Molecules in an Early Lysosomal Compartment,”J. Immunol. 151:3988-3998 (1993).
Heddini, et al., “Enrichment of Immunoglobulin Binding Plasmodium Falciparum-Infected Erythrocytes Using Anti-Immunoglobulin Coated Magnetic Beads,”Am. J. Trop. Med Hyg. 59:663-666 (1998).
Neefjes, et al., “The Biosynthetic Pathway of MHC Class II but not Class I Molecules Intersects the Endocytic Route,”Cell61:171-183 (1990).
Pileri, et al., “Binding of Hepatitus C Virus to CD81,”Science282:938-941 (1998).
Raposos, et al., “B Lymphocytes Secrete Antigen-Presenting Vesicles,”J. Exp. Med. 183:1161-1172 (1996).
Tulp, et al., “Isolation and Characterization of the Intracellular MHC Class II Compartment,”Nature369:120-126 (1994).
Abrignani Sergio
Pileri Piero
Lucas Zachariah
Novartis AG
Robins Roberta
Seka Mark
LandOfFree
Preparation of purified exosomes comprising HCV RNA does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Preparation of purified exosomes comprising HCV RNA, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Preparation of purified exosomes comprising HCV RNA will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-4241647