Preparation of protein films

Compositions – Preservative agents – Anti-corrosion

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260112B, 424101, 424107, B01J 1300

Patent

active

045487367

ABSTRACT:
A method to prepare protein films from protein gels is disclosed which utilizes the process of osmosis to remove excess fluid from protein gels without destroying the structural integrity of the protein. The method is conducted by first preparing a protein gel in a solvent, then contacting the gel with one side of a semipermeable membrane permeable to the solvent in which the gel was prepared, next adding a concentrated polymer solution to the other side of the membrane which membrane is impermeable to the polymer so as to cause movement of solvent from the gel, through the membrane, and into the polymer solution, and thus removing solvent from the gel for a period of time sufficient to contract the gel to a desired thickness.

REFERENCES:
patent: 2576006 (1951-11-01), Ferry et al.
patent: 4347841 (1982-09-01), Benyo et al.
Ferry et al., "Fibrin Clots, Fibrin Films . . . " Journal of Clinical Investigation, vol. 23, 1944, pp. 566-572.
Bailey et al., "Fibrin Films in Neurosurgery . . . " Journal of Clinical Investigation, vol. 23, 1944, pp. 597-600.
Ferry et al., "Human Fibrin in the Form of an Elastic Film" American Chemical Society Journal, vol. 69, 1947, pp. 400-409.
Clark et al., "Electron Microscopy of Network Structures . . . " International Journal of Peptide Protein Research, vol. 17, 1981, pp. 380-392.
Miyazaki et al., "Use of Fibrin Film as a Carrier for Drug Delivery . . . ", Chemical Pharm. Bulletin, vol. 30, 1982, pp. 3405-3407.

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