Preparation of protected amines or alkylated amino acids

Details Preparation of protected amines or alkylated amino acids Preparation of protected amines or alkylated amino acids

1995-12-04

1997-11-04

Raymond, Richard L.

Chemistry: natural resins or derivatives; peptides or proteins;

Peptides of 3 to 100 amino acid residues

Synthesis of peptides

546304, 562433, 562571, 562575, 564386, 564401, 564445, 564481, 564484, C07C20900

Patent

active

056841329

ABSTRACT:
The present invention relates to a process for preparing protected amines or amino acids. The invention furthermore relates to the use of tocopheryl radicals or radicals derived therefrom as protective groups for amines and amino acids, and to compounds obtained in this process as intermediates and to processes for preparing dipeptides and oligopeptides.

REFERENCES:
Green et al., Protective Groups in Organic Synthesis, 2nd ed., New York, 1991.
Organic Reactions, vol. 4, pp. 174-255, 1948.
Nakamura et al., Chem. Abst., vol. 76, No. 7, Feb. 14, 1972, abst. No. 34055f, p. 302.
Skinner et al., J. of Med. Chem., vol. 10, No. 4, Jul. 1967, pp. 657-661.
Rosenau et al., Tetrahedron, vol. 51, No. 29, Jun. 17, 1995, pp. 7919-7926, XP0000604701.
Rosenau et al., J. of Org. Chem., vol. 60, No. 25, Dec. 15, 1995, pp. 8120-8121, XP0000604700.

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