Preparation of prostaglandin precursors

Details Preparation of prostaglandin precursors Preparation of prostaglandin precursors

1974-05-08

1976-07-13

Gerstl, Robert

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

2604109R, 260413, 260468D, 260514D, 260514K, C07C 5100

Patent

active

039693910

ABSTRACT:
2-Alkoxy-4-hydroxy-5-oxocyclopent-1-eneheptanoic acid and its lower alkyl esters are reduced with metallic hydrides to yield the corresponding 3-hydroxy-5-oxo-cyclopent-1-eneheptanoic acid and its esters. The latter compounds are valuable intermediates in the preparation of pharmacologically active prostaglandin derivatives.

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