Preparation of polymorphically pure terfenadine

Details Preparation of polymorphically pure terfenadine Preparation of polymorphically pure terfenadine

1987-06-30

1988-05-03

Milestone, Norma S.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C07D21122

Patent

active

047421754

ABSTRACT:
Polymorphically pure terfenadine, 1-(p-tert-butylphenyl)-4-[4'-(.alpha.-hydroxydiphenylmethyl)-1'-piperidiny l]-butanol, is prepared by carefully controlled recrystallization methods.

REFERENCES:
patent: 3878217 (1975-04-01), Carr et al.

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