Preparation of pharmaceutically active particles

Details Preparation of pharmaceutically active particles Preparation of pharmaceutically active particles

1998-09-04

1999-12-07

Page, Thurman K.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Particulate form

424494, 424493, 424489, 424497, 424474, 424479, 424480, 424482, A61K 916, A61K 928

Patent

active

059979054

ABSTRACT:
The present invention provides a core of predominately microcrystalline cellulose, on which an active drug is layered onto the core via solution coating. The coated particles have a narrower particle size distribution than coated granules provided by other processes. An optional final coating of a pharmaceutically acceptable polymeric coating is provided to provide tastemaking or controlled release, and protection of the drug-layered particles.

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Avicel PH Microcrystalline Cellulose, NJ, Ph.Eur., JP, BP, FMC Corp.
Avicel PH Microcrystalline Cellulose, NJ, Ph.Eur., JP, BP,; Focut on Differentiated Prod. FMC Corp, Aug. 3, 1998.
Celphere Microcrystalline Cellulose Spheres, FMC Corp., Oct. 1995.

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