Preparation of pharmaceutical or cosmetic dispersions

Details Preparation of pharmaceutical or cosmetic dispersions Preparation of pharmaceutical or cosmetic dispersions

1989-03-15

1991-02-26

Lovering, Richard D.

Compositions

Preservative agents

Anti-corrosion

252312, 424 59, 366340, 514941, 514942, 514943, B01J 1300

Patent

active

049960040

ABSTRACT:
The invention relates to a process for the preparation of fine-particled, stable, pharmaceutical or cosmetic dispersions consisting of an aqueous phase and an organic phase which is insoluble or not completely soluble in water (oily phase) in which a pre-emulsion is prepared from the two phases by known emulsifying methods and in then pumped through a jet disperser, the temperature, the proportion of the aqueous and organic phases, and the pressure at the jet disperser being adjusted so that phase inversion of the emulsion is effected in the jet disperser at the same time as homogenization and fine dispersion, and in the course of which all the pressure energy is consumed in the dispersing zone and the dispersion leaves as a non-directional stream.

REFERENCES:
patent: 1496858 (1924-06-01), Knollenberg
patent: 1707466 (1929-04-01), Volck
patent: 2254049 (1941-08-01), Schutte
patent: 2524590 (1950-10-01), Boe
patent: 2665206 (1954-01-01), Bradley
patent: 2803565 (1957-08-01), Sagar
patent: 3137623 (1964-06-01), Gessler
patent: 3954658 (1976-05-01), Tsutsumi et al.

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