Preparation of pharmaceutical and other matrix systems by solid-

Details Preparation of pharmaceutical and other matrix systems by solid- Preparation of pharmaceutical and other matrix systems by solid-

1990-11-06

1993-06-01

Page, Thurman K.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Matrices

424485, 424486, 424487, 424488, 424441, 514948, 426384, 426385, 426524, A61K 914

Patent

active

052157563

ABSTRACT:
A method is disclosed for preparing pharmaceutical and other matrix systems that comprises solidifying a matrix composition dissolved or dispersed in a first solvent and subsequently contacting the solidified matrix with a second solvent that is substantially miscible with the first solvent at a temperature lower than the solidification point of the first solvent, the matrix components being substantially insoluble in the second solvent, whereby the first solvent is substantially removed resulting in a usable matrix.

REFERENCES:
patent: 4812445 (1989-03-01), Eden
patent: 4840796 (1989-06-01), Sweet
patent: 4851392 (1989-07-01), Shaw
patent: 4882154 (1989-11-01), Yang
patent: 4940588 (1990-07-01), Sparks
patent: 4946684 (1990-08-01), Blank et al.

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