Preparation of oxygenated ambroxides

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing heterocyclic carbon compound having only o – n – s,...

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131277, 549458, C12P 1704

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active

045857377

ABSTRACT:
In a method for the production of an agent for modifying a smoke-flavor, ambroxide is contacted with a microbial culture to effect a transformation of at least a proportion of the ambroxide to a product comprising at least one oxygenated derivative of ambroxide. The said product may comprise at least one of the compounds A, B and C, each as defined in the specification. The respective Compound, (particularly Compound A), may be extracted from said product for incorporation with a smoking material. Thus a smoke-flavor modifying agent produced by the aforesaid method for incorporation with, or included in, a smoking material or smoking article may comprise at least one compound of the aforesaid group.
The loading level of the said agent may be within a range of 0.1 to 100 parts per million or, suitably, of 0.5 to 10 parts per million, of the said smoking material.

REFERENCES:
patent: 2905575 (1959-09-01), Giles
patent: 2905576 (1959-09-01), Schumacher
patent: 2978365 (1961-04-01), Schumacher
Cambie et al., Australian J. Chem vol. 23, pp. 1439-1455, (1974).

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