Preparation of optically clear serum

Details Preparation of optically clear serum Preparation of optically clear serum

1975-06-13

1976-05-11

Wolk, Morris O.

Chemistry: physical processes

Physical processes

Crystallization

252408, 260112B, G01N 3316

Patent

active

039559254

ABSTRACT:
A stable optically clear serum is prepared for use in the preparation of standards and quality control reference material for the assay of human serum components. Prebeta lipoproteins, beta lipoproteins and chylomicrons are removed from human serum by specific precipitation. The serum resulting from the process disclosed retains its optical clarity upon freezing, lyophilization and reconstitution with aqueous media. Bovine lipoproteins are added to restore desired levels of cholesterol and triglycerides.

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Jonas, J. Bio. Chem., Vol. 247, No. 21, pp. 7767-7772, Nov. 1972.

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